Cross-platform comparability of microarray technology: Intra-platform consistency and appropriate data analysis procedures are essential
نویسندگان
چکیده
منابع مشابه
Intra-Platform Repeatability and Inter-Platform Comparability of MicroRNA Microarray Technology
Over the last decade, DNA microarray technology has provided a great contribution to the life sciences. The MicroArray Quality Control (MAQC) project demonstrated the way to analyze the expression microarray. Recently, microarray technology has been utilized to analyze a comprehensive microRNA expression profiling. Currently, several platforms of microRNA microarray chips are commercially avail...
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MOTIVATION Cross-platform microarray analysis is an increasingly important research tool, but researchers still lack open source tools for storing, integrating and analyzing large amounts of microarray data obtained from different array platforms. RESULTS An open source integrated microarray database and analysis suite, WebArrayDB (http://www.webarraydb.org), has been developed that features ...
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SUMMARY Microarrays are commonly used to detect changes in gene expression between different biological samples. For this purpose, many analysis tools have been developed that offer visualization, statistical analysis and more sophisticated analysis methods. Most of these tools are designed specifically for messenger RNA microarrays. However, today, more and more different microarray platforms ...
متن کاملIntegrative Array Analyzer: a software package for analysis of cross-platform and cross-species microarray data
The rapid accumulation of microarray data translates into an urgent need for tools to perform integrative microarray analysis. Integrative Array Analyzer is a comprehensive analysis and visualization software toolkit, which aims to facilitate the reuse of the large amount of cross-platform and cross-species microarray data. It is composed of the data preprocess module, the co-expression analysi...
متن کاملIntra- and inter- platform renormalization and analysis of microarray data from the NCBI GEO database
Background The availability of large repositories for microarray data such as NCBI GEO makes analysis across the entire set of available experiments an attractive prospect. However, large scale comparison of expression levels from microarrays is hindered by quality control, technology differences, and a lack of standardized interand intraplatform normalization procedures. This study proposes a ...
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ژورنال
عنوان ژورنال: BMC Bioinformatics
سال: 2005
ISSN: 1471-2105
DOI: 10.1186/1471-2105-6-s2-s12